Welcome to the Centre for Therapeutic Target Validation

For biomedical researchers who need to identify a biological target for a new therapy, the Centre for Therapeutic Target Validation (CTTV) is a public-private initiative to generate evidence on the validity of therapeutic targets based on genome-scale experiments and analysis. The CTTV is working to create an R&D framework that applies to a wide range of human diseases, and is committed to sharing its data openly with the scientific community.


Thursday, 27 March, 2014
A pioneering public-private research initiative between GSK, the European Bioinformatics Institute and the Wellcome Trust Sanger Institute is to harness the power of ‘big data’ and genome sequencing to improve the success rate for discovering new medicines. The new Centre for Therapeutic Target Validation will share its data openly in the interests of accelerating drug discovery.


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Jobs at the CTTV

Wellcome Trust Sanger Institute and EMBL-EBI Faculty

Initially the CTTV has been founded on seed funding from GSK combined with core expertise drawn from the three founding partners.  It is envisaged that the Centre will develop over a 3-5 year period into a sustainable scientific and financial entity comprising a core scientific population of circa 50 individuals housed in dedicated space on the Wellcome Trust Genome Campus, Hinxton, Cambridge.

The parties now wish to identify a head for the CTTV to provide inspiring leadership and direction, to drive the development of an ambitious strategy and to assemble the scientific talent necessary to deliver the Centre’s vision.      

You will have an international reputation as a scientific thought leader and an impeccable research record in a scientific area relevant to target validation. Coupled with this will be the experience and knowledge necessary to implement strategies to advance target validation and translational research. Ideally you will have led multidisciplinary scientific teams and collaborations within academia or industry and have displayed the skills required for a successful track record in securing external funding, including public and private sources. Enthusiastic and committed with high personal energy and drive you will be an excellent communicator coupled with the ability to inspire others with your vision for the Centre.

The role will have an initial five year tenure and be accountable to the CTTV Governance Board.  The role holder will be a full member of WTSI and EBI Faculty and will be regarded as a key member of GSK’s scientific leadership community, centred in nearby Stevenage.